Nano-based approach to combat emerging viral (NIPAH virus) infection

  • Rout George Kerry
  • , Santosh Malik
  • , Yisehak Tsegaye Redda
  • , Sabuj Sahoo
  • , Jayanta Kumar Patra
  • , Sanatan Majhi

Research output: Contribution to journalReview articlepeer-review

107 Scopus citations

Abstract

Emergence of new virus and their heterogeneity are growing at an alarming rate. Sudden outburst of Nipah virus (NiV) has raised serious question about their instant management using conventional medication and diagnostic measures. A coherent strategy with versatility and comprehensive perspective to confront the rising distress could perhaps be effectuated by implementation of nanotechnology. But in concurrent to resourceful and precise execution of nano-based medication, there is an ultimate need of concrete understanding of the NIV pathogenesis. Moreover, to amplify the effectiveness of nano-based approach in a conquest against NiV, a list of developed nanosystem with antiviral activity is also a prerequisite. Therefore the present review provides a meticulous cognizance of cellular and molecular pathogenesis of NiV. Conventional as well several nano-based diagnosis experimentations against viruses have been discussed. Lastly, potential efficacy of different forms of nano-based systems as convenient means to shield mankind against NiV has also been introduced.

Original languageEnglish
Pages (from-to)196-220
Number of pages25
JournalNanomedicine: Nanotechnology, Biology, and Medicine
Volume18
DOIs
StatePublished - Jun 2019

Keywords

  • Antiviral
  • Diagnostics
  • Nanomedicine
  • Nipah virus
  • Virucide

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