Abstract
Cures for advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) are rare and difficult. We report a case of pathologically confirmed complete remission of HCC induced by hepatic arterial infusion chemotherapy (HAIC). A 45-year-old male patient had a massive HCC in the right lobe of the liver and tumor thrombus in the right and main portal veins. He achieved a partial response after two cycles of HAIC with 5-fluorouracil (750 mg/m2) and cisplatin (25 mg/m2). After the completion of six cycles he received a curative partial hepatectomy, and histopathology revealed complete necrosis without any viable tumor cell. He was in good health at a 4-month follow-up. These results suggest that this regimen is a promising therapeutic modality for the treatment of advanced HCC with PVTT.
Original language | English |
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Pages (from-to) | 266-269 |
Number of pages | 4 |
Journal | Gut and Liver |
Volume | 4 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2010 |
Keywords
- 5-fluorouracil
- Chemotherapy
- Complete remission
- Hepatocellular carcinoma
- Portal vein tumor thrombosis