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Phenylpropanolamine contained in cold remedies and risk of hemorrhagic stroke

  • B. W. Yoon
  • , H. J. Bae
  • , K. S. Hong
  • , S. M. Lee
  • , B. J. Park
  • , K. H. Yu
  • , M. K. Han
  • , Y. S. Lee
  • , D. K. Chung
  • , J. M. Park
  • , S. W. Jeong
  • , B. C. Lee
  • , K. H. Cho
  • , J. S. Kim
  • , S. H. Lee
  • , K. M. Yoo
  • Seoul National University
  • Inje University
  • Hallym University
  • Kyungpook National University
  • Eulji University
  • Chonnam National University
  • Kosin University

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

In this study, we sought to elucidate whether phenylpropanolamine (PPA) in cold remedies (small and divided doses) increases the risk of hemorrhagic stroke (HS). PPA exposure significantly increased the risk, and the risk was much higher in women. In women, linear trends were also found in recency, duration, and dosage of PPA exposure. PPA contained in cold remedies increases the risk of HS, particularly in women.

Original languageEnglish
Pages (from-to)146-149
Number of pages4
JournalNeurology
Volume68
Issue number2
DOIs
StatePublished - Jan 2007

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