Poly(norepinephrine): Ultrasmooth material-independent surface chemistry and nanodepot for nitric oxide

Seonki Hong; Jihoon Kim; Yun Suk Na; Junghong Park; Sunjin Kim; Kaushik Singha; Gun Il Im; Dong Keun Han; Won Jong Kim; Haeshin Lee

doi:10.1002/anie.201301646

Poly(norepinephrine): Ultrasmooth material-independent surface chemistry and nanodepot for nitric oxide

Seonki Hong
, Jihoon Kim
, Yun Suk Na
, Junghong Park
, Sunjin Kim
, Kaushik Singha
, Gun Il Im
, Dong Keun Han
, Won Jong Kim
, Haeshin Lee

Department of Medicine

Korea Advanced Institute of Science and Technology
Pohang University of Science and Technology
Korea Institute of Science and Technology

Research output: Contribution to journal › Article › peer-review

244 Scopus citations

Abstract

Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. The pNE layer containing DHBA-NE serves to store and release small therapeutics such as nitric oxide.

Original language	English
Pages (from-to)	9187-9191
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	35
DOIs	https://doi.org/10.1002/anie.201301646
State	Published - 26 Aug 2013

Keywords

bioinspired chemistry
drug delivery
nitric oxide
polymers
surface chemistry

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10.1002/anie.201301646

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abstract = "Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. The pNE layer containing DHBA-NE serves to store and release small therapeutics such as nitric oxide.",

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doi = "10.1002/anie.201301646",

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T2 - Ultrasmooth material-independent surface chemistry and nanodepot for nitric oxide

AU - Hong, Seonki

AU - Kim, Jihoon

AU - Na, Yun Suk

AU - Park, Junghong

AU - Kim, Sunjin

AU - Singha, Kaushik

AU - Im, Gun Il

AU - Han, Dong Keun

AU - Kim, Won Jong

AU - Lee, Haeshin

PY - 2013/8/26

Y1 - 2013/8/26

N2 - Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. The pNE layer containing DHBA-NE serves to store and release small therapeutics such as nitric oxide.

AB - Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. The pNE layer containing DHBA-NE serves to store and release small therapeutics such as nitric oxide.

KW - bioinspired chemistry

KW - drug delivery

KW - nitric oxide

KW - polymers

KW - surface chemistry

UR - https://www.scopus.com/pages/publications/84882987455

U2 - 10.1002/anie.201301646

DO - 10.1002/anie.201301646

M3 - Article

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AN - SCOPUS:84882987455

SN - 1433-7851

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 35

ER -

Poly(norepinephrine): Ultrasmooth material-independent surface chemistry and nanodepot for nitric oxide

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Keywords

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