Postoperative neurocognitive disorders in ambulatory surgery: a narrative review

Junyong In, Brian Chen, Hansu Bae, Sakura Kinjo

Research output: Contribution to journalReview articlepeer-review

Abstract

Postoperative neurocognitive disorders (PoNCDs), such as postoperative delirium and cognitive dysfunction or decline can occur after surgery, especially in older patients. This significantly affects patient morbidity and surgical outcomes. Among various risk factors, recent studies have shown that preoperative frailty is associated with developing these conditions. Although the mechanisms underlying PoNCDs remain unclear, neuroinflammation appears to play an important role in their development. For the prevention and treatment of PoNCDs, medication modification, a balanced diet, and prehabilitation and rehabilitation programs have been suggested. The risk of developing PoNCDs is thought to be lower in ambulatory patients. However, owing to technological advancements, an increasing number of older and sicker patients are undergoing more complex surgeries and are often not closely monitored after discharge. Therefore, equal attention should be paid to all patient populations. This article presents an overview of PoNCDs and highlights issues of particular interest for ambulatory surgery.

Original languageEnglish
Pages (from-to)493-502
Number of pages10
JournalKorean Journal of Anesthesiology
Volume77
Issue number5
DOIs
StatePublished - Oct 2024

Keywords

  • Ambulatory surgery
  • Cognition disorders
  • Cognitive dysfunction
  • Delirium
  • Outpatient
  • Postoperative complications

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