Potentials of raspberry ketone as a natural antioxidant

Sung Ho Lim, Chang Ik Choi

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Oxidative stress is closely linked to various diseases, and many studies have been con-ducted to determine how to reduce this stress. In particular, efforts are being made to find potential antioxidants from natural products. Studies have shown that raspberry ketone (RK; 4-(4-hydroxy-phenyl)-2-butanone) has various pharmacological activities. This review summarizes the antioxi-dant activities of RK and their underlying mechanisms. In several experimental models, it was proven that RK exhibits antioxidant properties through increasing total antioxidant capacity (TAC); upregulating antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT); and improving lipid peroxidation. In conclusion, research about RK’s antioxidant activities is directly or indirectly related to its other various physiological activities. Further studies at the clinical level will be able to verify the value of RK as an effective antioxidant, functional health food, and therapeutic agent.

Original languageEnglish
Article number482
Pages (from-to)1-13
Number of pages13
JournalAntioxidants
Volume10
Issue number3
DOIs
StatePublished - Mar 2021

Keywords

  • Antioxidant enzyme activity
  • Lipid peroxidation
  • Natural antioxidant
  • Raspberry ketone
  • Total antioxidant capacity

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