Prospective Validation of the Objective Prognostic Score for Advanced Cancer Patients in Diverse Palliative Settings

Hyun Jung Jho; Sang Yeon Suh; Seok Joon Yoon; Sanghee Shiny Lee; Hong Yup Ahn; Takashi Yamaguchi; Masanori Mori; Isseki Maeda; Mika Baba; Tatsuya Morita

doi:10.1016/j.jpainsymman.2016.03.015

Prospective Validation of the Objective Prognostic Score for Advanced Cancer Patients in Diverse Palliative Settings

Hyun Jung Jho
, Sang Yeon Suh
, Seok Joon Yoon
, Sanghee Shiny Lee
, Hong Yup Ahn
, Takashi Yamaguchi
, Masanori Mori
, Isseki Maeda
, Mika Baba
, Tatsuya Morita

National Cancer Center Korea
Chungnam National University
Dongguk University
Kobe University
Seirei Hamamatsu General Hospital
The University of Osaka
Saito Yukoukai Hospital
Seirei Mikatahara General Hospital

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Context Prognostication is an essential part of palliative care to aid decision making and negotiate goals of care. The Objective Prognostic Score (OPS) is an easy-to-use prognosticating tool to predict survival among far-advanced cancer patients in palliative care units (PCUs) in Korea. Objectives This study aimed to prospectively validate the OPS for advanced cancer patients in the palliative care teams (PCTs), PCUs, and home-based palliative care (HPC) in Japan. Methods This was a substudy of a multicenter prospective cohort study that was conducted to validate and compare prognostic tools among advanced cancer patients in Japan. Participants’ survival was calculated according to OPS 3 as a cutoff for predicting survival of less than three weeks. Overall accuracy and area under the receiver operator characteristic curves of OPS 3 were calculated for PCT, PCU, and HPC, respectively. Results A total of 1146 cases (PCTs 441, PCUs 519, and HPCs 186 cases) were included in final analyses. The overall accuracy of OPS 3 for predicting three-week survival ranged from 0.70 to 0.78 across diverse palliative care settings. The c-statistics ranged from 0.742 to 0.808 across three settings. Participants in the PCT showed the highest overall accuracy and c-statistics for OPS. Conclusion The OPS can be used for prognostication among advanced cancer patients in PCT, PCU, and HPC settings.

Original language	English
Pages (from-to)	420-427
Number of pages	8
Journal	Journal of Pain and Symptom Management
Volume	52
Issue number	3
DOIs	https://doi.org/10.1016/j.jpainsymman.2016.03.015
State	Published - 1 Sep 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer
Objective Prognostic Score
palliative care
prognostication
survival

Access to Document

10.1016/j.jpainsymman.2016.03.015

Cite this

@article{e5062d983c24403da721b6fe2d6ecdde,

title = "Prospective Validation of the Objective Prognostic Score for Advanced Cancer Patients in Diverse Palliative Settings",

abstract = "Context Prognostication is an essential part of palliative care to aid decision making and negotiate goals of care. The Objective Prognostic Score (OPS) is an easy-to-use prognosticating tool to predict survival among far-advanced cancer patients in palliative care units (PCUs) in Korea. Objectives This study aimed to prospectively validate the OPS for advanced cancer patients in the palliative care teams (PCTs), PCUs, and home-based palliative care (HPC) in Japan. Methods This was a substudy of a multicenter prospective cohort study that was conducted to validate and compare prognostic tools among advanced cancer patients in Japan. Participants{\textquoteright} survival was calculated according to OPS 3 as a cutoff for predicting survival of less than three weeks. Overall accuracy and area under the receiver operator characteristic curves of OPS 3 were calculated for PCT, PCU, and HPC, respectively. Results A total of 1146 cases (PCTs 441, PCUs 519, and HPCs 186 cases) were included in final analyses. The overall accuracy of OPS 3 for predicting three-week survival ranged from 0.70 to 0.78 across diverse palliative care settings. The c-statistics ranged from 0.742 to 0.808 across three settings. Participants in the PCT showed the highest overall accuracy and c-statistics for OPS. Conclusion The OPS can be used for prognostication among advanced cancer patients in PCT, PCU, and HPC settings.",

keywords = "Cancer, Objective Prognostic Score, palliative care, prognostication, survival",

author = "Jho, \{Hyun Jung\} and Suh, \{Sang Yeon\} and Yoon, \{Seok Joon\} and Lee, \{Sanghee Shiny\} and Ahn, \{Hong Yup\} and Takashi Yamaguchi and Masanori Mori and Isseki Maeda and Mika Baba and Tatsuya Morita",

note = "Publisher Copyright: {\textcopyright} 2016 American Academy of Hospice and Palliative Medicine",

year = "2016",

month = sep,

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doi = "10.1016/j.jpainsymman.2016.03.015",

language = "English",

volume = "52",

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publisher = "Elsevier Inc.",

number = "3",

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TY - JOUR

T1 - Prospective Validation of the Objective Prognostic Score for Advanced Cancer Patients in Diverse Palliative Settings

AU - Jho, Hyun Jung

AU - Suh, Sang Yeon

AU - Yoon, Seok Joon

AU - Lee, Sanghee Shiny

AU - Ahn, Hong Yup

AU - Yamaguchi, Takashi

AU - Mori, Masanori

AU - Maeda, Isseki

AU - Baba, Mika

AU - Morita, Tatsuya

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Context Prognostication is an essential part of palliative care to aid decision making and negotiate goals of care. The Objective Prognostic Score (OPS) is an easy-to-use prognosticating tool to predict survival among far-advanced cancer patients in palliative care units (PCUs) in Korea. Objectives This study aimed to prospectively validate the OPS for advanced cancer patients in the palliative care teams (PCTs), PCUs, and home-based palliative care (HPC) in Japan. Methods This was a substudy of a multicenter prospective cohort study that was conducted to validate and compare prognostic tools among advanced cancer patients in Japan. Participants’ survival was calculated according to OPS 3 as a cutoff for predicting survival of less than three weeks. Overall accuracy and area under the receiver operator characteristic curves of OPS 3 were calculated for PCT, PCU, and HPC, respectively. Results A total of 1146 cases (PCTs 441, PCUs 519, and HPCs 186 cases) were included in final analyses. The overall accuracy of OPS 3 for predicting three-week survival ranged from 0.70 to 0.78 across diverse palliative care settings. The c-statistics ranged from 0.742 to 0.808 across three settings. Participants in the PCT showed the highest overall accuracy and c-statistics for OPS. Conclusion The OPS can be used for prognostication among advanced cancer patients in PCT, PCU, and HPC settings.

AB - Context Prognostication is an essential part of palliative care to aid decision making and negotiate goals of care. The Objective Prognostic Score (OPS) is an easy-to-use prognosticating tool to predict survival among far-advanced cancer patients in palliative care units (PCUs) in Korea. Objectives This study aimed to prospectively validate the OPS for advanced cancer patients in the palliative care teams (PCTs), PCUs, and home-based palliative care (HPC) in Japan. Methods This was a substudy of a multicenter prospective cohort study that was conducted to validate and compare prognostic tools among advanced cancer patients in Japan. Participants’ survival was calculated according to OPS 3 as a cutoff for predicting survival of less than three weeks. Overall accuracy and area under the receiver operator characteristic curves of OPS 3 were calculated for PCT, PCU, and HPC, respectively. Results A total of 1146 cases (PCTs 441, PCUs 519, and HPCs 186 cases) were included in final analyses. The overall accuracy of OPS 3 for predicting three-week survival ranged from 0.70 to 0.78 across diverse palliative care settings. The c-statistics ranged from 0.742 to 0.808 across three settings. Participants in the PCT showed the highest overall accuracy and c-statistics for OPS. Conclusion The OPS can be used for prognostication among advanced cancer patients in PCT, PCU, and HPC settings.

KW - Cancer

KW - Objective Prognostic Score

KW - palliative care

KW - prognostication

KW - survival

UR - https://www.scopus.com/pages/publications/84979774550

U2 - 10.1016/j.jpainsymman.2016.03.015

DO - 10.1016/j.jpainsymman.2016.03.015

M3 - Article

C2 - 27387346

AN - SCOPUS:84979774550

SN - 0885-3924

VL - 52

SP - 420

EP - 427

JO - Journal of Pain and Symptom Management

JF - Journal of Pain and Symptom Management

IS - 3

ER -

Prospective Validation of the Objective Prognostic Score for Advanced Cancer Patients in Diverse Palliative Settings

Abstract

UN SDGs

Keywords

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