Proteasome inhibitory, antioxidant, and synergistic antibacterial and anticandidal activity of green biosynthesized magnetic Fe3O4 nanoparticles using the aqueous extract of corn (Zea mays L.) ear leaves

Jayanta Kumar Patra, Md Sarafat Ali, In Gyung Oh, Kwang Hyun Baek

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Herein, Fe3O4 nanoparticles synthesized using aqueous extract of corn ear leaves were investigated for proteasome inhibitory activity, antioxidant activity, synergistic antibacterial, and anticandidal potential. The UV-Vis spectrum displayed an absorption band at 355 nm that indicated the formation of nano-sized Fe3O4 particles. Vibrating sample magnetometer analysis revealed its superparamagnetic nature. Fe3O4 nanoparticles exhibited strong proteasome inhibitory potential and antioxidant activity and exerted strong synergistic antibacterial and anticandidal activity. Its significant proteasome inhibitory potential could be useful in cancer treatment and drug delivery. Furthermore, strong antioxidant, antibacterial, and anticandidal activity make them a promising candidate for biomedical and pharmaceutical applications.

Original languageEnglish
Pages (from-to)349-356
Number of pages8
JournalArtificial Cells, Nanomedicine and Biotechnology
Volume45
Issue number2
DOIs
StatePublished - 17 Feb 2017

Keywords

  • Antibacterial
  • anticandidal
  • antioxidant
  • corn ear leaves
  • Fe3O4 nanoparticles
  • proteasome inhibitory

Fingerprint

Dive into the research topics of 'Proteasome inhibitory, antioxidant, and synergistic antibacterial and anticandidal activity of green biosynthesized magnetic Fe3O4 nanoparticles using the aqueous extract of corn (Zea mays L.) ear leaves'. Together they form a unique fingerprint.

Cite this