Random Serum Cortisol as a Predictor for Survival of Terminally Ill Patients With Cancer: A Preliminary Study

Hyo Min Kim, Kyung Sang Ha, In Cheol Hwang, Hong Yup Ahn, Chang Ho Youn

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Although previous research found that serum cortisol levels were associated with cancer prognosis, it is unclear whether this association remains robust even at the very end of life of patients with cancer. We conducted a retrospective chart review of 125 patients with terminal cancer to investigate the role of random serum cortisol levels in predicting the remaining life expectancy. The high random cortisol group had a significantly shorter survival time than the low random cortisol group (7.5 vs 26 days). After adjusting for potential confounders, key factors such as poor performance status, hypoalbuminemia, and high random cortisol level are associated with poor survival. Our results suggest that the random serum cortisol level is an independent predictor of survival time of patients with terminally ill cancer.

Original languageEnglish
Pages (from-to)281-285
Number of pages5
JournalAmerican Journal of Hospice and Palliative Medicine
Volume33
Issue number3
DOIs
StatePublished - 1 Apr 2016

Keywords

  • end of life
  • hospice care
  • prognosis
  • random serum cortisol
  • survival
  • terminal cancer

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