Recent advances in anticancer chemotherapeutics based upon azepine scaffold

Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong Shin Chang, Kyeong Lee, Yongseok Choi

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

Original languageEnglish
Pages (from-to)539-557
Number of pages19
JournalAnti-Cancer Agents in Medicinal Chemistry
Volume16
Issue number5
DOIs
StatePublished - 1 May 2016

Keywords

  • Anticancer agents
  • Azepane scaffold
  • Chemotherapeutics
  • Histone deacetylases
  • Hormone modulators
  • Kinase inhibitors
  • Phototherapeutic agents
  • Tubulin inhibitors

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