TY - JOUR
T1 - Risk Assessment and Determination of Heavy Metals in Home Meal Replacement Products by Using Inductively Coupled Plasma Mass Spectrometry and Direct Mercury Analyzer
AU - Hwang, Hee Jeong
AU - Hwang, Gyo Ha
AU - Ahn, So Min
AU - Kim, Yong Yeon
AU - Shin, Han Seung
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/2/1
Y1 - 2022/2/1
N2 - This study quantified six heavy metals (Pb, Cd, As, Sn, Hg, and Me-Hg) in home meal replacement products. Satisfactory linearity (R2 > 0.99), recovery (80.65–118.02%), limits of detection (0.02–2.81 µg/kg), limits of quantification (0.05–8.51 µg/kg), accuracy (80.49–119.87%), precision (0.26–14.93%), standard uncertainty (0.082–0.321%) and relative standard uncertainty (0.084–0.320%) of the six heavy metals were obtained. The average concentration of the six heavy metals was 8.87 µg/kg. Heavy metal concentrations were converted to food intake data of 0.009 µg/kg to recalculate the 95th percentile food intake data (g/day) of individual heavy metals. These were then divided by age group to evaluate the average exposure to heavy metals and determine the 95th percentile of exposure from daily intake and for the whole population, of home meal replacement products. The chronic daily intake amount of six heavy metals was 1.60 × 10−2 µg/kg/day. Based on total chronic daily intake values, the risk and margin of exposure of each of the heavy metals was 9.13 × 107, demonstrating that intake associated with home meal replacement products is negligible.
AB - This study quantified six heavy metals (Pb, Cd, As, Sn, Hg, and Me-Hg) in home meal replacement products. Satisfactory linearity (R2 > 0.99), recovery (80.65–118.02%), limits of detection (0.02–2.81 µg/kg), limits of quantification (0.05–8.51 µg/kg), accuracy (80.49–119.87%), precision (0.26–14.93%), standard uncertainty (0.082–0.321%) and relative standard uncertainty (0.084–0.320%) of the six heavy metals were obtained. The average concentration of the six heavy metals was 8.87 µg/kg. Heavy metal concentrations were converted to food intake data of 0.009 µg/kg to recalculate the 95th percentile food intake data (g/day) of individual heavy metals. These were then divided by age group to evaluate the average exposure to heavy metals and determine the 95th percentile of exposure from daily intake and for the whole population, of home meal replacement products. The chronic daily intake amount of six heavy metals was 1.60 × 10−2 µg/kg/day. Based on total chronic daily intake values, the risk and margin of exposure of each of the heavy metals was 9.13 × 107, demonstrating that intake associated with home meal replacement products is negligible.
KW - Direct mercury analyzer
KW - Heavy metal
KW - Home meal replacement
KW - Inductively coupled plasma mass spectrometry
KW - Risk assessment
UR - http://www.scopus.com/inward/record.url?scp=85124744926&partnerID=8YFLogxK
U2 - 10.3390/foods11040504
DO - 10.3390/foods11040504
M3 - Article
AN - SCOPUS:85124744926
SN - 2304-8158
VL - 11
JO - Foods
JF - Foods
IS - 4
M1 - 504
ER -