TY - JOUR
T1 - Risk factor analysis for development of asymptomatic carotid stenosis in Koreans
AU - Lim, Yun Jeong
AU - Kim, Young Wook
AU - Choe, Yeon Hyen
AU - Ki, Chang Seok
AU - Park, Sue Kyung
PY - 2006/2
Y1 - 2006/2
N2 - Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS ≥30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At sub-group analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.
AB - Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS ≥30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At sub-group analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.
KW - Atherosclerosis
KW - Carotid stenosis
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=33144460425&partnerID=8YFLogxK
U2 - 10.3346/jkms.2006.21.1.15
DO - 10.3346/jkms.2006.21.1.15
M3 - Article
AN - SCOPUS:33144460425
SN - 1011-8934
VL - 21
SP - 15
EP - 19
JO - Journal of Korean Medical Science
JF - Journal of Korean Medical Science
IS - 1
ER -