Risk factor analysis for development of asymptomatic carotid stenosis in Koreans

Yun Jeong Lim, Young Wook Kim, Yeon Hyen Choe, Chang Seok Ki, Sue Kyung Park

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS ≥30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At sub-group analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalJournal of Korean Medical Science
Volume21
Issue number1
DOIs
StatePublished - Feb 2006

Keywords

  • Atherosclerosis
  • Carotid stenosis
  • Risk factors

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