Abstract
Sphingosylphosphorylcholine (SPC) is a unique type of lysosphingolipid found in some diseases, and has been studied in cardiovascular, neurological, and inflammatory phenomena. In particular, SPC's studies on cancer have been conducted mainly in terms of effects on cancer cells, and relatively little consideration has been given to aspects of tumor microenvironment. This review summarizes the effects of SPC on cancer and tumor microenvironment, and presents the results and prospects of modulators that regulate the various actions of SPC.
| Original language | English |
|---|---|
| Article number | 1696 |
| Journal | Cancers |
| Volume | 11 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2019 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Inflammatory
- Lysosphingolipids
- Neurological
- Sphingosylphosphorylcholine
- Tumor microenvironment
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