Stem cell responses to nanotopography

Siyeon Park, Gun Il Im

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations

Abstract

Cells interact with various nanoscaled topographical and biochemical cues in their cellular macromolecular environment. Nanotopography recreates or mimic the cellular macromolecular environment in vitro. The influence of material surface topography on the behavior of adherent cells has been studied. Current techniques enable various kinds of nanopatterned surface to be generated and applied to cells. The purpose of this review is to provide an overview of nanotopography and its surface patterns, and introduce nanoto-pography effects on cell behavior including cell attachment, proliferation, and cell differentiation with particular emphasis on musculoskeletal regeneration.

Original languageEnglish
Pages (from-to)1238-1245
Number of pages8
JournalJournal of Biomedical Materials Research - Part A
Volume103
Issue number3
DOIs
StatePublished - 1 Mar 2015

Keywords

  • Musculoskeletal regeneration
  • Nanotopography
  • Stem cells

Fingerprint

Dive into the research topics of 'Stem cell responses to nanotopography'. Together they form a unique fingerprint.

Cite this