Stereoselectivity in the condensation reactions between malate enolate and imines to 2-pyrrolidinone derivatives

  • Deok Chan Ha
  • , Kyeong Soon Yun
  • , Hye Sang Park
  • , Won Keun Choung
  • , Young Eun Kwon

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Enolate dianion of diethyl (S)-malate was stereoselectively condensed with nonenoiizable N-arylimines to give 2-pyrrolidinone derivatives. The presence of HMPA changes the diastereoselectivity of this cyclization reaction.

Original languageEnglish
Pages (from-to)8445-8448
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number46
DOIs
StatePublished - 13 Nov 1995

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