The AGTR2 (RS11091046) Gene Polymorphism is Associated with Cycling Performance in Korean Cyclists

Seok Ki Min; Seung Taek Lim; Kwangkyu Lee; Jieun Kim; Eonho Kim; Eunbin Jee

doi:10.15857/ksep.2021.00451

The AGTR2 (RS11091046) Gene Polymorphism is Associated with Cycling Performance in Korean Cyclists

Seok Ki Min, Seung Taek Lim, Kwangkyu Lee, Jieun Kim, Eonho Kim, Eunbin Jee

Department of Physical Education

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE: This study aimed to investigate the association between AGTR2 (rs11091046 A>C) gene polymorphism and athletic performance. METHODS: The Korean national team cyclists enrolled in the study performed 30-second Wingate test (peak power, mean power, and power drop), one-repetition maximum (squat and bench press), and isokinetic dynamometer (60° extensor and flexor in both legs) to examine the power/sprint performance between the C and A alleles. RESULTS: The physical characteristics showed no significant difference between the C and A alleles. Comparison of physical fitness tests in cyclists revealed no significant difference between the two alleles in one-repetition maximum and isokinetic dynamometer. However, the C allele had a significantly higher peak power (10.46±0.82 vs. 9.92±0.57, p=.016) and mean power (8.30±0.48 vs. 7.95±0.47, p=.022) than A allele in the Wingate test. CONCLUSIONS: Our results demonstrate that the AGTR2 gene C allele is associated with the power/sprint performance of the Korean national team cyclists.

Original language	English
Pages (from-to)	105-109
Number of pages	5
Journal	Exercise Science
Volume	31
Issue number	1
DOIs	https://doi.org/10.15857/ksep.2021.00451
State	Published - Feb 2022

Keywords

AGTR2
Alleles
Athletic performance
Genotype
Polymorphism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.15857/ksep.2021.00451

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title = "The AGTR2 (RS11091046) Gene Polymorphism is Associated with Cycling Performance in Korean Cyclists",

abstract = "PURPOSE: This study aimed to investigate the association between AGTR2 (rs11091046 A>C) gene polymorphism and athletic performance. METHODS: The Korean national team cyclists enrolled in the study performed 30-second Wingate test (peak power, mean power, and power drop), one-repetition maximum (squat and bench press), and isokinetic dynamometer (60° extensor and flexor in both legs) to examine the power/sprint performance between the C and A alleles. RESULTS: The physical characteristics showed no significant difference between the C and A alleles. Comparison of physical fitness tests in cyclists revealed no significant difference between the two alleles in one-repetition maximum and isokinetic dynamometer. However, the C allele had a significantly higher peak power (10.46±0.82 vs. 9.92±0.57, p=.016) and mean power (8.30±0.48 vs. 7.95±0.47, p=.022) than A allele in the Wingate test. CONCLUSIONS: Our results demonstrate that the AGTR2 gene C allele is associated with the power/sprint performance of the Korean national team cyclists.",

keywords = "AGTR2, Alleles, Athletic performance, Genotype, Polymorphism",

author = "Min, {Seok Ki} and Lim, {Seung Taek} and Kwangkyu Lee and Jieun Kim and Eonho Kim and Eunbin Jee",

note = "Publisher Copyright: {\textcopyright} 2022 Korean Society of Exercise Physiology.",

year = "2022",

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doi = "10.15857/ksep.2021.00451",

language = "English",

volume = "31",

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T1 - The AGTR2 (RS11091046) Gene Polymorphism is Associated with Cycling Performance in Korean Cyclists

AU - Min, Seok Ki

AU - Lim, Seung Taek

AU - Lee, Kwangkyu

AU - Kim, Jieun

AU - Kim, Eonho

AU - Jee, Eunbin

PY - 2022/2

Y1 - 2022/2

N2 - PURPOSE: This study aimed to investigate the association between AGTR2 (rs11091046 A>C) gene polymorphism and athletic performance. METHODS: The Korean national team cyclists enrolled in the study performed 30-second Wingate test (peak power, mean power, and power drop), one-repetition maximum (squat and bench press), and isokinetic dynamometer (60° extensor and flexor in both legs) to examine the power/sprint performance between the C and A alleles. RESULTS: The physical characteristics showed no significant difference between the C and A alleles. Comparison of physical fitness tests in cyclists revealed no significant difference between the two alleles in one-repetition maximum and isokinetic dynamometer. However, the C allele had a significantly higher peak power (10.46±0.82 vs. 9.92±0.57, p=.016) and mean power (8.30±0.48 vs. 7.95±0.47, p=.022) than A allele in the Wingate test. CONCLUSIONS: Our results demonstrate that the AGTR2 gene C allele is associated with the power/sprint performance of the Korean national team cyclists.

AB - PURPOSE: This study aimed to investigate the association between AGTR2 (rs11091046 A>C) gene polymorphism and athletic performance. METHODS: The Korean national team cyclists enrolled in the study performed 30-second Wingate test (peak power, mean power, and power drop), one-repetition maximum (squat and bench press), and isokinetic dynamometer (60° extensor and flexor in both legs) to examine the power/sprint performance between the C and A alleles. RESULTS: The physical characteristics showed no significant difference between the C and A alleles. Comparison of physical fitness tests in cyclists revealed no significant difference between the two alleles in one-repetition maximum and isokinetic dynamometer. However, the C allele had a significantly higher peak power (10.46±0.82 vs. 9.92±0.57, p=.016) and mean power (8.30±0.48 vs. 7.95±0.47, p=.022) than A allele in the Wingate test. CONCLUSIONS: Our results demonstrate that the AGTR2 gene C allele is associated with the power/sprint performance of the Korean national team cyclists.

KW - AGTR2

KW - Alleles

KW - Athletic performance

KW - Genotype

KW - Polymorphism

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JO - Exercise Science

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The AGTR2 (RS11091046) Gene Polymorphism is Associated with Cycling Performance in Korean Cyclists

Abstract

Keywords

UN SDGs

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