Abstract
This paper examines the effect of polydopamine (PD) coating of gold nanorods (GNRs) on their performance as a matrix material for laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF-MS) analysis. Bare GNRs and PD-coated GNRs (PD@GNRs) were utilized for LDI-TOF-MS analyses of small molecules and synthetic polymers, and the influences of PD-coating were mechanistically studied. Based on the results, we found that the PD-coating of GNRs suppressed the generation of undesired gold cluster ions, enhanced photothermal conversion and the LDI-TOF-MS efficiency, and expanded the working molecular weight range.
Original language | English |
---|---|
Pages (from-to) | 2372-2377 |
Number of pages | 6 |
Journal | The Analyst |
Volume | 142 |
Issue number | 13 |
DOIs | |
State | Published - 7 Jul 2017 |