TY - JOUR
T1 - Third-generation biomass for bioplastics
T2 - a comprehensive review of microalgae-driven polyhydroxyalkanoate production
AU - Saratale, Rijuta Ganesh
AU - Cho, Si Kyung
AU - Bharagava, Ram Naresh
AU - Patel, Anil Kumar
AU - Vivekanand, Vivekanand
AU - Bhatia, Shashi Kant
AU - Ferreira, Luiz Fernando Romanholo
AU - Shin, Han Seung
AU - Awasthi, Mukesh Kumar
AU - Chakrabortty, Sankha
AU - Kumar, Ramesh
AU - Saratale, Ganesh Dattatraya
N1 - Publisher Copyright:
© 2024 Alpha Creation Enterprise.
PY - 2024/12
Y1 - 2024/12
N2 - Bio-based plastics, primarily polyhydroxyalkanoates (PHAs), offer a hopeful alternative to petroleum-derived plastics. Third-generation (3G; microalgae/cyanobacteria) biomass has gained significant importance due to its rapid biomass productivity and metabolic versatility. Microalgae can produce PHAs by utilizing CO2 and wastewater, establishing them as highly promising and eco-friendly systems for bioplastic production. This comprehensive review presents comprehensive insights into microalgae-PHA production, from optimization of physicochemical and cultural conditions to effective PHA purification processes. The critical review also examines the latest advancements in cultivation strategies, metabolic engineering, and bioreactor developments, which may lead to more sustainable and progressive microalgal-based bioplastic accumulation. The effectiveness of algae biomass generation for PHA accumulation through integrated wastewater treatment has been addressed. This review examines the role of mathematical modeling and emerging artificial intelligence in advancing algae-based PHA production processes. Finally, the review concludes with a discussion of the economic and social challenges, life cycle analysis, and prospects for research and development of advanced microalgal-derived bioplastics production and predictions of potential solutions for economically feasible and sustainable microalgae-based PHA production at the industrial scale.
AB - Bio-based plastics, primarily polyhydroxyalkanoates (PHAs), offer a hopeful alternative to petroleum-derived plastics. Third-generation (3G; microalgae/cyanobacteria) biomass has gained significant importance due to its rapid biomass productivity and metabolic versatility. Microalgae can produce PHAs by utilizing CO2 and wastewater, establishing them as highly promising and eco-friendly systems for bioplastic production. This comprehensive review presents comprehensive insights into microalgae-PHA production, from optimization of physicochemical and cultural conditions to effective PHA purification processes. The critical review also examines the latest advancements in cultivation strategies, metabolic engineering, and bioreactor developments, which may lead to more sustainable and progressive microalgal-based bioplastic accumulation. The effectiveness of algae biomass generation for PHA accumulation through integrated wastewater treatment has been addressed. This review examines the role of mathematical modeling and emerging artificial intelligence in advancing algae-based PHA production processes. Finally, the review concludes with a discussion of the economic and social challenges, life cycle analysis, and prospects for research and development of advanced microalgal-derived bioplastics production and predictions of potential solutions for economically feasible and sustainable microalgae-based PHA production at the industrial scale.
KW - Bioreactor development
KW - Integrated wastewater treatment
KW - Machine learning
KW - Metabolic regulation
KW - Microalgae
KW - Polyhydroxyalkanoate production
UR - http://www.scopus.com/inward/record.url?scp=85211340265&partnerID=8YFLogxK
U2 - 10.18331/BRJ2024.11.4.5
DO - 10.18331/BRJ2024.11.4.5
M3 - Review article
AN - SCOPUS:85211340265
SN - 2292-8782
VL - 11
SP - 2256
EP - 2282
JO - Biofuel Research Journal
JF - Biofuel Research Journal
IS - 4
ER -
