TPAOH assisted size-tunable Gd2O3@mSi core-shell nanostructures for multifunctional biomedical applications

E. Pavitra; G. Seeta Rama Raju; Ganji Purnachandra Nagaraju; Goli Nagaraju; Young Kyu Han; Yun Suk Huh; Jae Su Yu

doi:10.1039/c7cc07975c

TPAOH assisted size-tunable Gd₂O₃@mSi core-shell nanostructures for multifunctional biomedical applications

E. Pavitra
, G. Seeta Rama Raju
, Ganji Purnachandra Nagaraju
, Goli Nagaraju
, Young Kyu Han
, Yun Suk Huh
, Jae Su Yu

Inha University
Kyung Hee University
Emory University

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We report a facile and large-scale synthesis of size-tunable and nontoxic mesoporous silica-coated Gd₂O₃:Eu³⁺ (Gd@mSi) core-shell nanostructures using a TPAOH assisted modified UHP technique. The role of TPAOH in controlling the particle size was evaluated. The potentiality of these Gd@mSi core-shell nanoparticles before and after folic acid conjugation was established by in vitro fluorescence microscopy of the U2OS cell lines for cancer imaging and therapy.

Original language	English
Pages (from-to)	747-750
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	7
DOIs	https://doi.org/10.1039/c7cc07975c
State	Published - 2018

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10.1039/c7cc07975c

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title = "TPAOH assisted size-tunable Gd2O3@mSi core-shell nanostructures for multifunctional biomedical applications",

abstract = "We report a facile and large-scale synthesis of size-tunable and nontoxic mesoporous silica-coated Gd2O3:Eu3+ (Gd@mSi) core-shell nanostructures using a TPAOH assisted modified UHP technique. The role of TPAOH in controlling the particle size was evaluated. The potentiality of these Gd@mSi core-shell nanoparticles before and after folic acid conjugation was established by in vitro fluorescence microscopy of the U2OS cell lines for cancer imaging and therapy.",

author = "E. Pavitra and \{Seeta Rama Raju\}, G. and Nagaraju, \{Ganji Purnachandra\} and Goli Nagaraju and Han, \{Young Kyu\} and Huh, \{Yun Suk\} and Yu, \{Jae Su\}",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c7cc07975c",

language = "English",

volume = "54",

pages = "747--750",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - TPAOH assisted size-tunable Gd2O3@mSi core-shell nanostructures for multifunctional biomedical applications

AU - Pavitra, E.

AU - Seeta Rama Raju, G.

AU - Nagaraju, Ganji Purnachandra

AU - Nagaraju, Goli

AU - Han, Young Kyu

AU - Huh, Yun Suk

AU - Yu, Jae Su

PY - 2018

Y1 - 2018

N2 - We report a facile and large-scale synthesis of size-tunable and nontoxic mesoporous silica-coated Gd2O3:Eu3+ (Gd@mSi) core-shell nanostructures using a TPAOH assisted modified UHP technique. The role of TPAOH in controlling the particle size was evaluated. The potentiality of these Gd@mSi core-shell nanoparticles before and after folic acid conjugation was established by in vitro fluorescence microscopy of the U2OS cell lines for cancer imaging and therapy.

AB - We report a facile and large-scale synthesis of size-tunable and nontoxic mesoporous silica-coated Gd2O3:Eu3+ (Gd@mSi) core-shell nanostructures using a TPAOH assisted modified UHP technique. The role of TPAOH in controlling the particle size was evaluated. The potentiality of these Gd@mSi core-shell nanoparticles before and after folic acid conjugation was established by in vitro fluorescence microscopy of the U2OS cell lines for cancer imaging and therapy.

UR - https://www.scopus.com/pages/publications/85040982025

U2 - 10.1039/c7cc07975c

DO - 10.1039/c7cc07975c

M3 - Article

C2 - 29308475

AN - SCOPUS:85040982025

SN - 1359-7345

VL - 54

SP - 747

EP - 750

JO - Chemical Communications

JF - Chemical Communications

IS - 7

ER -

TPAOH assisted size-tunable Gd₂O₃@mSi core-shell nanostructures for multifunctional biomedical applications

Abstract

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