TY - JOUR
T1 - Trends in Bacterial Skin Infections and their Antibiotic Susceptibility in Korea
T2 - a 13-year Single-center Study
AU - Jeong, Jong Heon
AU - Lee, Ji Young
AU - Lee, Seung Ho
AU - Lee, Ai Young
AU - Hong, Jong Soo
N1 - Publisher Copyright:
Copyright © 2020 by The Korean Society for Medical Mycology. All right reserved.
PY - 2020/9
Y1 - 2020/9
N2 - Background: The kinds and identification rates of major bacteria causing bacterial skin infections have changed steadily over time. Although studies of the causative pathogen changes over time have been reported worldwide, no follow-up studies of bacterial skin infections have been conducted in Korea since 2009. Objective: To investigate the changes in the identification rate and antibiotic susceptibility of causative pathogens of bacterial skin infections, especially S. aureus, over time in Korea. Methods: This study was conducted in outpatient clinics in 2006, 2009, 2012, 2015, and 2018, in which the data on age, sex, identification of bacteria, and susceptibility to antibiotics were retrospectively analyzed. Results: Of the 350 cases, except for suspected normal flora, 213 (60.9%) were positive for S. aureus, accounting for the highest percentage, followed by 22 (6.3%) for P. aeruginosa, 7 (2%) for Serratia marcescens, and 6 (1.7%) for Bacillus species, Enterococcus faecalis, and Staphylococcus lugdunensis. The identification rate of methicillin-resistant S. aureus (MRSA) increased from 2009 to 2015 and then decreased in 2018. Conclusion: The proportion of MRSA gradually increased from 2006 to 2015 but suddenly reversed in 2018, possibly due to improved education for infection prevention or changes in the virulence of the circulating strains of MRSA. Also, based on our findings, MRSA is currently susceptible to trimethoprim-sulfamethoxazole and vancomycin.
AB - Background: The kinds and identification rates of major bacteria causing bacterial skin infections have changed steadily over time. Although studies of the causative pathogen changes over time have been reported worldwide, no follow-up studies of bacterial skin infections have been conducted in Korea since 2009. Objective: To investigate the changes in the identification rate and antibiotic susceptibility of causative pathogens of bacterial skin infections, especially S. aureus, over time in Korea. Methods: This study was conducted in outpatient clinics in 2006, 2009, 2012, 2015, and 2018, in which the data on age, sex, identification of bacteria, and susceptibility to antibiotics were retrospectively analyzed. Results: Of the 350 cases, except for suspected normal flora, 213 (60.9%) were positive for S. aureus, accounting for the highest percentage, followed by 22 (6.3%) for P. aeruginosa, 7 (2%) for Serratia marcescens, and 6 (1.7%) for Bacillus species, Enterococcus faecalis, and Staphylococcus lugdunensis. The identification rate of methicillin-resistant S. aureus (MRSA) increased from 2009 to 2015 and then decreased in 2018. Conclusion: The proportion of MRSA gradually increased from 2006 to 2015 but suddenly reversed in 2018, possibly due to improved education for infection prevention or changes in the virulence of the circulating strains of MRSA. Also, based on our findings, MRSA is currently susceptible to trimethoprim-sulfamethoxazole and vancomycin.
KW - Antibiotics
KW - Bacterial skin infections
KW - MRSA
KW - S. aureus
UR - http://www.scopus.com/inward/record.url?scp=85147232297&partnerID=8YFLogxK
U2 - 10.17966/JMI.2020.25.3.51
DO - 10.17966/JMI.2020.25.3.51
M3 - Article
AN - SCOPUS:85147232297
SN - 1226-4709
VL - 25
SP - 51
EP - 56
JO - Journal of Mycology and Infection
JF - Journal of Mycology and Infection
IS - 3
ER -