Two cases of unusual manifestations of secondary syphilis accompanied by human immunodeficiency virus infection

We report two cases of unusual manifestations of secondary syphilis accompanied by human immunodeficencieng virus infection. The first case is a 57-year-old heterosexual man with human immunodeficiency virus (HIV) seropositivity and unusual manifestations of secondary syphilis. The second case is a 28-year-old man presented with unusual cutaneous lesions of secondary syphilis. The following laboratory tests showed that the patient was seropositive for HIV. Both patients' cutaneous lesions resembled those of a patient with Reiter's syndrome such as keratoderma blennorrhagicum and circinate balanitis. The VDRL test of the first case showed the prozone phenomenon (false-negative in undiluted specimen).