Understanding the mode of action of L-nucleosides as antiviral agents: A molecular modeling approach

Kyeong Lee; Youhoon Chong; Chung K. Chu

doi:10.1081/NCN-100002311

Understanding the mode of action of L-nucleosides as antiviral agents: A molecular modeling approach

Kyeong Lee
, Youhoon Chong
, Chung K. Chu

Department of Pharmacy

University of Georgia

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Computer modeling studies have been performed on the several pairs of D- and L-nucleoside inhibitors with the HIV-1 RT model. Additionally, clinically important M184V mutation, which confers the viral resistance against 3TC and FTC, were studied by the same modeling system.

Original language	English
Pages (from-to)	385-388
Number of pages	4
Journal	Nucleosides, Nucleotides and Nucleic Acids
Volume	20
Issue number	4-7
DOIs	https://doi.org/10.1081/NCN-100002311
State	Published - 2001

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10.1081/NCN-100002311

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title = "Understanding the mode of action of L-nucleosides as antiviral agents: A molecular modeling approach",

abstract = "Computer modeling studies have been performed on the several pairs of D- and L-nucleoside inhibitors with the HIV-1 RT model. Additionally, clinically important M184V mutation, which confers the viral resistance against 3TC and FTC, were studied by the same modeling system.",

author = "Kyeong Lee and Youhoon Chong and Chu, \{Chung K.\}",

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AU - Chong, Youhoon

AU - Chu, Chung K.

PY - 2001

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AB - Computer modeling studies have been performed on the several pairs of D- and L-nucleoside inhibitors with the HIV-1 RT model. Additionally, clinically important M184V mutation, which confers the viral resistance against 3TC and FTC, were studied by the same modeling system.

UR - https://www.scopus.com/pages/publications/0034850951

U2 - 10.1081/NCN-100002311

DO - 10.1081/NCN-100002311

M3 - Article

C2 - 11563052

AN - SCOPUS:0034850951

SN - 1525-7770

VL - 20

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JO - Nucleosides, Nucleotides and Nucleic Acids

JF - Nucleosides, Nucleotides and Nucleic Acids

IS - 4-7

ER -

Understanding the mode of action of L-nucleosides as antiviral agents: A molecular modeling approach

Abstract

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