TY - JOUR
T1 - Update on Chitosan-Based Hydrogels
T2 - Preparation, Characterization, and Its Antimicrobial and Antibiofilm Applications
AU - Thirupathi, Kokila
AU - Raorane, Chaitany Jayaprakash
AU - Ramkumar, Vanaraj
AU - Ulagesan, Selvakumari
AU - Santhamoorthy, Madhappan
AU - Raj, Vinit
AU - Krishnakumar, Gopal Shankar
AU - Phan, Thi Tuong Vy
AU - Kim, Seong Cheol
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2023/1
Y1 - 2023/1
N2 - Chitosan is a prominent biopolymer in research for of its physicochemical properties and uses. Each year, the number of publications based on chitosan and its derivatives increases. Because of its comprehensive biological properties, including antibacterial, antioxidant, and tissue regeneration activities, chitosan and its derivatives can be used to prevent and treat soft tissue diseases. Furthermore, chitosan can be employed as a nanocarrier for therapeutic drug delivery. In this review, we will first discuss chitosan and chitosan-based hydrogel polymers. The structure, functionality, and physicochemical characteristics of chitosan-based hydrogels are addressed. Second, a variety of characterization approaches were used to analyze and validate the physicochemical characteristics of chitosan-based hydrogel materials. Finally, we discuss the antibacterial, antibiofilm, and antifungal uses of supramolecular chitosan-based hydrogels. This review study can be used as a base for future research into the production of various types of chitosan-based hydrogels in the antibacterial and antifungal fields.
AB - Chitosan is a prominent biopolymer in research for of its physicochemical properties and uses. Each year, the number of publications based on chitosan and its derivatives increases. Because of its comprehensive biological properties, including antibacterial, antioxidant, and tissue regeneration activities, chitosan and its derivatives can be used to prevent and treat soft tissue diseases. Furthermore, chitosan can be employed as a nanocarrier for therapeutic drug delivery. In this review, we will first discuss chitosan and chitosan-based hydrogel polymers. The structure, functionality, and physicochemical characteristics of chitosan-based hydrogels are addressed. Second, a variety of characterization approaches were used to analyze and validate the physicochemical characteristics of chitosan-based hydrogel materials. Finally, we discuss the antibacterial, antibiofilm, and antifungal uses of supramolecular chitosan-based hydrogels. This review study can be used as a base for future research into the production of various types of chitosan-based hydrogels in the antibacterial and antifungal fields.
KW - antibacterial activity
KW - antibiofilm
KW - antifungal materials
KW - chitosan-based hydrogel
KW - structural characterization
UR - https://www.scopus.com/pages/publications/85146756803
U2 - 10.3390/gels9010035
DO - 10.3390/gels9010035
M3 - Review article
AN - SCOPUS:85146756803
SN - 2310-2861
VL - 9
JO - Gels
JF - Gels
IS - 1
M1 - 35
ER -