Using elastic light scattering of red blood cells to detect infection of malaria parasite

Seungjun Lee, Wei Lu

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

To develop noninvasive diagnosis of malaria, we studied the light-scattering pattern of healthy and 2 Plasmodium falciparum malaria parasitized red blood cells. By measuring the wavelength-dependent scattering at discrete angles of both forward and backward directions, we found that the signal can clearly distinguish between healthy and ring stage infected red blood cells. In particular, we demonstrated the first backward scattering measurement, which enables elastic light scattering as a promising noninvasive diagnostic tool for malaria.

Original languageEnglish
Article number6020751
Pages (from-to)150-155
Number of pages6
JournalIEEE Transactions on Biomedical Engineering
Volume59
Issue number1
DOIs
StatePublished - Jan 2012

Keywords

  • Biomedical engineering
  • light scattering
  • noninvasive diagnosis
  • red blood cell

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