Using elastic light scattering of red blood cells to detect infection of malaria parasite

Seungjun Lee; Wei Lu

doi:10.1109/TBME.2011.2168398

Using elastic light scattering of red blood cells to detect infection of malaria parasite

Seungjun Lee
, Wei Lu

Department of Mechanical, Robotics and Energy Engineering

University of Michigan, Ann Arbor

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

To develop noninvasive diagnosis of malaria, we studied the light-scattering pattern of healthy and 2 Plasmodium falciparum malaria parasitized red blood cells. By measuring the wavelength-dependent scattering at discrete angles of both forward and backward directions, we found that the signal can clearly distinguish between healthy and ring stage infected red blood cells. In particular, we demonstrated the first backward scattering measurement, which enables elastic light scattering as a promising noninvasive diagnostic tool for malaria.

Original language	English
Article number	6020751
Pages (from-to)	150-155
Number of pages	6
Journal	IEEE Transactions on Biomedical Engineering
Volume	59
Issue number	1
DOIs	https://doi.org/10.1109/TBME.2011.2168398
State	Published - Jan 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Biomedical engineering
light scattering
noninvasive diagnosis
red blood cell

Access to Document

10.1109/TBME.2011.2168398

Cite this

@article{75fec903566e4c1d855a29332d4d351e,

title = "Using elastic light scattering of red blood cells to detect infection of malaria parasite",

abstract = "To develop noninvasive diagnosis of malaria, we studied the light-scattering pattern of healthy and 2 Plasmodium falciparum malaria parasitized red blood cells. By measuring the wavelength-dependent scattering at discrete angles of both forward and backward directions, we found that the signal can clearly distinguish between healthy and ring stage infected red blood cells. In particular, we demonstrated the first backward scattering measurement, which enables elastic light scattering as a promising noninvasive diagnostic tool for malaria.",

keywords = "Biomedical engineering, light scattering, noninvasive diagnosis, red blood cell",

author = "Seungjun Lee and Wei Lu",

year = "2012",

month = jan,

doi = "10.1109/TBME.2011.2168398",

language = "English",

volume = "59",

pages = "150--155",

journal = "IEEE Transactions on Biomedical Engineering",

issn = "0018-9294",

publisher = "IEEE Computer Society",

number = "1",

}

TY - JOUR

T1 - Using elastic light scattering of red blood cells to detect infection of malaria parasite

AU - Lee, Seungjun

AU - Lu, Wei

PY - 2012/1

Y1 - 2012/1

N2 - To develop noninvasive diagnosis of malaria, we studied the light-scattering pattern of healthy and 2 Plasmodium falciparum malaria parasitized red blood cells. By measuring the wavelength-dependent scattering at discrete angles of both forward and backward directions, we found that the signal can clearly distinguish between healthy and ring stage infected red blood cells. In particular, we demonstrated the first backward scattering measurement, which enables elastic light scattering as a promising noninvasive diagnostic tool for malaria.

AB - To develop noninvasive diagnosis of malaria, we studied the light-scattering pattern of healthy and 2 Plasmodium falciparum malaria parasitized red blood cells. By measuring the wavelength-dependent scattering at discrete angles of both forward and backward directions, we found that the signal can clearly distinguish between healthy and ring stage infected red blood cells. In particular, we demonstrated the first backward scattering measurement, which enables elastic light scattering as a promising noninvasive diagnostic tool for malaria.

KW - Biomedical engineering

KW - light scattering

KW - noninvasive diagnosis

KW - red blood cell

UR - https://www.scopus.com/pages/publications/84555197045

U2 - 10.1109/TBME.2011.2168398

DO - 10.1109/TBME.2011.2168398

M3 - Article

C2 - 21926010

AN - SCOPUS:84555197045

SN - 0018-9294

VL - 59

SP - 150

EP - 155

JO - IEEE Transactions on Biomedical Engineering

JF - IEEE Transactions on Biomedical Engineering

IS - 1

M1 - 6020751

ER -

Using elastic light scattering of red blood cells to detect infection of malaria parasite

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this